This screencast explains a basic strategy for solving memory leaks with JProfiler.
There is an older version of this screencast from 2009 that is not accurate for the heap walker anymore but that shows other useful features in JProfiler.
This screen cast shows how the class loaders probe can be used to debug class loading and to solve class loader memory leaks.
In the screencast below, I explain the different reference views in the heap walker.
There is a newer version of this screen cast.
This version is outdated with respect to the heap walker, but it also shows useful features outside of the heap walker.